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Nicholls, R

The tripeptide itself functions as a signaling molecule capable of influencing gene expression across hundreds of genes involved in tissue repair and regeneration, extending well beyond simple copper delivery

4.3.1 Disrupting tumor-derived immunosuppression: Targeting Wnt5a in BRAF-mutant melanoma In BRAF-mutant melanomas, Wnt5a overexpression drives stromal fibrosis and DC tolerization, creating an immune-excluded TME

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Furthermore, human-induced pluripotent stem cell-derived EVs exert cardioprotective effects through the transport of miR-20a-5p and miR-19a-3p while enhancing -oxidation gene expression [98]

Baird SK, Hampton MB, Gieseg SP